IL9R HEK293
CBP74597
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| I. Background | |
| IL9R基因编码白细胞介素-9受体(IL-9R),是一种I型细胞因子受体,特异性介导IL-9的生物学效应。功能性IL-9受体复合体由IL-9Rα链(CD129)与IL-2受体γ链(γc)共同组成,后者也是IL-2、IL-4、IL-7、IL-15等细胞因子受体共用的亚基。配体结合后,该受体激活JAK1/JAK3激酶和STAT1/3/5等信号通路,参与调控T细胞增殖、肥大细胞活化及IgE生成。该基因定位于X和Y染色体的拟常染色体区,在哮喘、过敏性炎症及非小细胞肺癌等疾病中受到关注。 | |
| II. Description | |
| IL9R HEK293细胞,在 HEK293细胞的基础上,稳定表达 IL9R 。 | |
| III. Introduction | |
| Expressed gene: | IL9R |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant IL9R HEK293 constitutively expressing IL9R. |
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